Testosterone Cypionate injection is administered intramuscularly. The injection contains testosterone cypionate which is a white or creamy white powder that is odorless too. Testosterone cypionate is oil-soluble 17(beta) cyclopentylpropionate ester of testosterone which is a naturally occurring growth hormone in the body. Testosterone cypionate is insoluble in water. It is soluble in alcohol and chloroform. Testosterone cypionate is a testosterone ester and testosterone esters are less polar than free testosterone. When injected intramuscularly, testosterone is absorbed slowly.
Testosterone is inactivated in the liver. Excretion of a dose of testosterone is 90% done in the urine through glucoronic and sulphuric acid conjugates of testosterone. 6% is excreted in the feces. In the feces it is excreted in unconjugated form. Testosterone cypionate has a half-life of 8 days when it is injected intramuscularly. When there is a deficiency of endogenous testosterone, testosterone cypionate is injected in patients to cover the deficiency.
In the absence or deficiency of testosterone certain conditions can be developed. These include hypogonadism, vanishing testes syndrome and orchidectomey. To overcome such medical conditions it becomes necessary that testosterone be administered exogenously in synthetic forms. Natural production of testosterone may be diminished in athletes and bodybuilders who have undergone a steroid cycle lately. Testosterone cypionate helps in overcoming the testosterone deficiency.
The drug should not be administered in patients who have known hypersensitivity to the drug, in males who have breast cancer, males who have known or suspected prostate cancer, pregnant women and patients who have renal, cardiac or hepatic disease. Extreme care must be taken when using this drug. It should never be self-prescribed. A professional doctor or medical practitioners should be consulted before this drug could be used.
It should be worth noting here that the drug should be immediately discontinued if hypercalcemia occurs in patients who are immobilized. Since it is an androgenic steroid it is suggested that prolonged use of the drug should be avoided. If taken for prolonged periods of time conditions such as hepatic adenomas, hepatocellular carcinoma and pelliosis hepatis may develop. Gynecomastia may also be developed especially in those patients who are already being treated for hypogonadism.